The CDC currently advises that you should not be vaccinated if you have an allergy to any of the components of the vaccine (See the ingredient list FAQ below). If you have had a severe or immediate allergic reaction of any severity within 4 hours after getting the first COVID-19 shot, you should not get the second shot.
The CDC and FDA on Friday Jan 22nd published anaphylaxis data for Moderna’s vaccine in MMWR. Of more than 4 million first doses administered between late December and early January, 10 cases of anaphylaxis were reported to the Vaccine Adverse Event Reporting System. This translates to 2.5 cases per million doses. All but one case occurred within 15 minutes of vaccination. None of the patients died. For comparison, early data suggested an anaphylaxis rate of 11.1 per million doses with the Pfizer-BioNTech vaccine — a rate that a CDC official characterized as “exceedingly rare.”
If you indicate a history of a serious allergic reaction on your CDC Vaccine Questionnaire, you may be asked to schedule a televisit with your physician/PCP prior to scheduling your vaccine. You may also be asked to wait for 30 minutes after your vaccine to be observed for any reactions to the vaccine.
The most accurate and current information regarding allergies and the COVID-19 vaccine can be found from the CDC and the American College of Allergy, Asthma, and Immunology below: